Sample Size Estimation
Introduction: In general, sample size calculation is
conducted through a pre-study power analysis. The purpose is to select
an appropriate sample size in achieving a desired power for correctly detection
of a pre-specified clinical meaningful difference at a given level of
significance. This study/tool will provide statistical procedures for
determination of sample size required not only for testing equality, but also for testing non-inferiority/superiority,
equivalence (similarity) and some survival analysis and phase II clinical trials designs that
are commonly employed at various phases of clinical development. As a handful
tool, it is very useful for clinical scientists and biostatisticians in the
pharmaceutical industry, regulatory agencies, academia, and other scientists
who are related fields of clinical development.
This program helps users to determine
sample sizes for a broad range of statistical techniques, including the
study of means, proportions, survival analysis, phase II clinical trials and
some general cases (others).
DIRECTIONS:
- Choose one of techniques from "Means",
"Proportions", "Survival Analysis" and “Phase II
Clinical Trials” in following table
- From the table the technique appeared that you
selected, please select one of specified case you are interested
- The selected sample size calculator will be appeared by
a new window, then enjoy to use calculator to determine your required
sample size!
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