Strength and Expertise
The Department has expertise in:
- Conducting Phase II-IV clinical trials in anesthesia (including obstetric, trauma, regional, cardiothoracic, neurosurgical, and pediatric), perioperative (including traditional Chinese medicine and acupuncture), pain and intensive care medicine;
- Performing invasive and noninvasive hemodynamic and coagulation monitoring;
- Performing neurophysiologic and cerebral function monitoring;
- Carrying out advanced neuropsychology tests;
- Using advanced real-time ultrasound techniques for regional anesthesia;
- Conducting quality of life research for perioperative, pain and intensive care medicine;
- Performing complex pharmacokinetic modeling (NONMEM, Kinetica);
- Systematic analysis (by Cochrane editor)
- Epidemiological studies
The department has participated in planning and endpoint adjudication for major international trials.
Special Facility and Equipment
- Dedicated laboratory with HPLC MS/MS for analysis of drug assays (including antibiotics, antiviral agents, intravenous anesthetics, opioids, antiemetics, etc.)
- Dedicated IT officers for developing web based CRF, data entry.
Collaboration, Partners and Multi-centre Trials Capability
- Overseas collaborations:
- China: Peking Union Medical Center
- Europe: Institute of Clinical Research, Odense University, Denmark, European Society of Intensive Care Medicine, University of Birmingham
- Australia: Australian and New Zealand College of Anaesthetists (ANZCA) Trial group, Australian and New Zealand Intensive Care Society Clinical Trials Group, University of Queensland
- US: University of California, San Francisco
- Canada: McMaster University, Hamilton; University of Western Ontario, London Ontanrio
- Singapore: Intensive Care Units, Tan Tock Seng Hospital
- Saudi Arabia: King Saud Bin Abdulaziz University for Health Sciences, Riyadh
- Industrial collaboration:
- Glaxo-Smith-Kline
- Novartis
- Pfizer
- Progenics
- Nova Nordisk
- Eisai
- Collaborators in local institutions:
- United Christian Hospital
- Tuen Mum Hospital
- North District Hospital
- Alice Ho Miu Ling Nethersole Hospital
- Kwong Wah Hospital
Clinical Trials Monitored and/or Audited by Industry, FDA and local RGC etc.
- Glaxo-Smith-Kline on antiemetic drug trials (September, 2006)
- Canadian Cardiovascular Collaboration, HGH-McMaster Clinic, Population Health Research Institute, McMaster University, Canada (April, 2007)
- Treatment of Candidaemia (Pfizer)
- Treatment of MRSA pneumonia (Pfizer)
- Sepsis treatment (Eisai)
